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    Diflucan: How and Why Patients Take It Have you ever heard of Diflucan? If you want to start taking it, the first thing that should be understood is that this medication is designed to treat all kinds of oral and vaginal fungal infections if they are resulted by Candida. Sometimes doctors prescribe it to those patients who need to prevent and treat different Candida infections while undergoing bone-marrow transplantation, radiation or chemotherapy. List of Adverse Effects You also need to realize that the use of Diflucan is associated with certain side effects, but there is no drug that comes without them. Basically, in rare cases patients may suffer from the following symptoms: In a few occasions, people may experience the symptoms of serious allergies, such as swelling, skin rash, drowsiness and others. Besides, irregular heartbeats and liver issues are associated with the intake of Diflucan. Basic Information about This Medicine It belongs to a class of anti-fungal meds, and it functions by preventing the production of cell membranes in fungi. Therapy may be instituted before the results of the cultures and other laboratory studies are known; however, once these results become available, anti-infective therapy should be adjusted accordingly. Fluconazole is not recommended for use in children and adolescents under the age of 16 years, unless antifungal treatment is imperative, and no suitable alternative agent exists, due to insufficient safety and efficacy (see section 5.2). Coadministration of terfenadine is contraindicated in patients receiving Fluconazole 150mg capsule at multiple doses of 400 mg per day or higher based upon results of a multiple dose interaction study. Coadministration of other medicinal products known to prolong the QT interval and which are metabolised via the cytochrome P450 (CYP) 3A4 such as cisapride, astemizole, pimozide, quinidine and erythromycin are contraindicated in patients receiving fluconazole (see sections 4.4 and 4.5). Fluconazole 150 mg capsule has been associated with rare cases of serious hepatic toxicity including fatalities, primarily in patients with serious underlying medical conditions. In cases of fluconazole-associated hepatotoxicity, no obvious relationship to total daily dose, duration of therapy, sex or age of patient has been observed. Fluconazole hepatotoxicity has usually been reversible on discontinuation of therapy.

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    So you think you have a yeast infection and you buy an over-the-counter (OTC) treatment, but four days later you are still very itchy/irritated/burning like crazy. First of all you need this background information: If you were right then there is a 85-90% chance that you should be better. The next step, for most women, is to call their GYNO and ask for fluconazole, known by many under the brand name Diflucan, or to retreat with a OTC topical. If you guessed correctly and aren’t better more of the same (i.e. trying fluconazole/Diflucan or another OTC medication) is not likely to be any better because the oral and topicals work in the same way. If you are not feeling better after treatment (which will happen 75% of the time just looking at the statistics) there are five possible scenarios: Put another way, if 100 women use OTC medication for vaginal yeast, 70 will have persistent symptoms because they never had yeast to begin with and 5 will still have persistent symptoms related to yeast. That means if you have persistent symptoms there is a 93% chance you never had yeast and a 7% chance that you did, but need further information to treat. The chance that more of the same will help is very slim. Other clinical pearls: A bad yeast infection can take seven days to feel a lot better, An antihistamine, like Zyrtec or Claritin, will help you feel better faster and a low dose topical steroid on the vulva (labia and vaginal opening) will also help if there is a lot of external irritation But the OTC always fails for me and the Diflucan always works! This is unlikely related to the type of medication (OTC vs prescription) and more a mechanical issue – some women place the vaginal medication too low in their vagina (if the tissues are really inflamed it can be harder to get high enough). Thrush Oral Capsule Containing Fluconazole is used for treating fungi infections in men and women. It contains the active ingredient Fluconazole which provides healing for genital thrush and infections of the vagina or penis. Please note: this treatment is not suitable for oral thrush. Women only If you are pregnant, suspect you might be pregnant or are breast-feeding. If you have any abnormal or irregular vaginal bleeding or a blood stained discharge. If you have vulval or vaginal sores, ulcers or blisters. If you are experiencing lower abdominal pain or burning sensation on passing water. The product should never be used again if the patient experiences a rash or anaphylaxis following the use of the drug.

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