C10403 is an aggressive and complex treatment regimen for adolescents and young adults (AYA) with ALL. The C10403 regimen is similar to treatment regimens given to pediatric patients (less than 18 y.o.) and is usually considered more aggressive than regimens given to adults (40 years or older). The entire C10403 chemotherapy regimen consists of 5 different treatment courses: induction (this page), consolidation, interim maintenance, delayed intensification, and maintenance. Each of the medications in C10403 are designed to target and kill acute lymphoblastic leukemia cells in the blood, bone marrow, or wherever else they may happen to be. Goals of therapy: C10403 induction is given to eliminate the majority of leukemia cells from the blood and bone marrow. Following induction, the remaining treatment courses are given to eliminate any remaining leukemia cells and maintain remission from the leukemia. The C10403 protocol is commonly given with the goal of cure. 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