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    Prednisolone is indicated in the management of all conditions deemed likely to benefit from short or long term glucocorticoid therapy. These include: Allergic states Severe, incapacitating allergies unresponsive to conventional treatment; asthma serum sickness; drug hypersensitivity reactions. Collagen disorders Eg systemic lupus erythematosus, polymyositis, polymyalgia rheumatica and temporal (giant cell) arteritis, mixed connective tissue disease syndrome, acute rheumatic carditis. Rheumatic disorders Usually given as an adjunctive therapy for short term administration during an acute episode or exacerbation of rheumatoid arthritis, psoriatic arthritis. Skin conditions Life-threatening or incapacitating skin conditions such as pemphigus and exfoliative dermatitis. Neoplastic disease Leukaemias and lymphomas in adults, acute leukaemia of childhood. Gastro-Intestinal disease During acute exacerbation in ulcerative colitis and regional ileitis (Crohn's Disease). Prednisolone is one of a group of medicines known as steroids; specifically, it is a glucocorticosteroid. Glucocorticosteroids occur naturally in the body, helping to maintain good body functioning and the health. Prednisolone is effective in the treatment of many different inflammatory diseases and conditions. Such diseases include autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, and ulcerative colitis), and skin, blood, respiratory, kidney, bowel, muscle, and joint problems. If left untreated, the inflammation may escalate and worsen your condition. By taking extra glucocorticoids, Prednisolone acts by reducing inflammation. Prednisolone is often taken in a tablet, which comes in a range of doses and in regular, gastro-resistant, and soluble forms.

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    There are a number of different conditions that you should tell your doctor about before he or she prescribes prednisone, including liver disease, kidney disease, thyroid disorder, diabetes, tuberculosis, osteoporosis, stomach ulcers, depression, or any sort of mental illness. Using prednisone or any other steroids for a long period of time can lead to bone loss (osteoporosis), particularly if you smoke and do not exercise on a regular basis. This medication has been known to cause low birth weight or birth defects for pregnant women who take it in their first trimester. It is important that you tell your doctor if you are pregnant or plan on getting pregnant while using prednisone. This medication absolutely needs to be used exactly as instructed by a physician. You will need to follow all of the directions on the bottle, and you can also ask your local pharmacist if you have any questions. The dosage of this medication that your doctor prescribes can change over time if you contract a serious illness or infection of some kind. Prednisolone belongs to a group of medicines called Steroids and their full name is Corticosteroids. These corticosteroids occur naturally in the body, and help to maintain health and well being. Boosting your body with extra corticosteroid (such as Prednisolone) is an effective way to treat various illnesses involving inflammation in the body. Prednisolone reduces this inflammation, which could otherwise go on making your condition worse. You must take this medicine regularly to get maximum benefit from it. Always take Prednisolone tablets exactly as your doctor has told you, especially if you are elderly. If you are not sure, check with your doctor or pharmacist.

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    Synthesis of enantiomerically pure S-−-propranolol from.